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Zhang J, Wang X, Vikash V, Ye Q, Wu D, Liu Y, et al
Given the redundant nature of immunosuppressive pathways in the TME, co-targeting the TIGIT/CD155 axis alongside PD-1 blockadepotentially facilitated by multi-payload nanomedicine delivery systemsrepresents a highly promising frontier for overcoming resistance and restoring robust antitumor immunity
At the same time, P5 prevented the accumulation of macrophages in eWAT contributing to decrease inflammation and insulin resistance 26
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