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Beyond hepatic steatosis, efruxifermin improved multiple metabolic and hepatic parameters, including increasing adiponectin levels and improved lipid profiles compared to placebo

These include nutritional guidance, physical activity, emotion regulation skills, and self-monitoring, which are core components of both post-bariatric and general obesity programs

However, these new emergent dual agonists need further investigation to understand the mechanisms of action, how to interact with the respective receptors, increase efficacy, and good safety profile [90,91,92,93,94]

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