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Faster absorption means more semaglutide reaching GLP-1 receptors in a shorter time window, and those receptors in the brain and gut respond accordingly

The pill expands treatment options for patients who prefer an oral alternative, but lifestyle support and medical follow-up remain critical components of care

Clinical studies Despite their thriving role in the treatment of obesity 214 , only seven studies investigated the effects of GLP-1RAs in eating disorders (Table 6), including some on their psychopathology in comorbid obesity 215,216,217 and others specifically in binge-eating disorder (BED) 217,218,219,220 , and we could not find any ongoing trial in this area

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The higher tirzepatide doses of 10 and 15 mg were noninferior compared to insulin glargine for the change in HbA1c (primary endpoint)