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doi: 10.1007/s12325-019-01101-6

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18 Support for the poorer bioavailability of cyano-B12 comes from a study comparing sublingual cyano- with methyl-B12 (both 1000 g per day), which found that both forms led to a normalisation of B12 status, but B12 levels increased significantly more in the methyl-B12 form compared with the cyano-B12 form, although the formulations also had other differences the former was a tablet, the latter a spray

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That level of neurogenesis enhancement is significant for any brain repair application, because the limiting factor in many neurological recovery scenarios is simply not having enough new neurons to replace those lost to injury or disease