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One of the more recent representatives of this drug class, and the one that has been shown to exert a superior effect to GLP-1 receptor agonists in humans, is LY3298176/tirzepatide, a synthetic linear peptide molecule containing 39 amino acids (Fig
This makes it a valuable tool for those looking to manage their weight, balance blood sugar levels, or improve gut health
Note there are 2 large randomized trials of semaglutide for Alzheimers disease expected to report out in 2026
Common side effects include : Diarrhea Vomiting Stomach pain Upset stomach or indigestion Dizziness Burping Flatulence Stomach flu-like symptoms Heartburn or acid reflux Common cold-like symptoms Hypoglycemia (low blood sugar) in people with type 2 diabetes More serious side effects are also possible but are less likely
IC 95%=0,58-0,95)
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