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Gallagher CM, Meliker JR

The GLP-1 receptor (GLP-1R) is expressed in pancreatic beta cells, the central nervous system, and the gastrointestinal tract

Looking ahead, with the integration of multidisciplinary fields (such as materials science, micro/nano energy, and artificial intelligence), implantable devices will evolve toward intelligence and personalization

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Although ectopic lipid accumulation in peripheral tissue appears to be the primary cause of insulin resistance, increased ER stress, inflammation, and reactive oxygen species levels, dysregulations of adipokines contribute to the pathogenesis of insulin resistance in liver and skeletal muscle