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Results from the Phase II clinical trial (NCT02970942) showed that after 72 weeks, 59% of patients in the 0.4 mg semaglutide group achieved NASH resolution without worsening liver fibrosis , a statistically significant result compared to 17% in the placebo group, meeting the primary clinical endpoint
Importantly, these criteria intentionally exclude peptide systems for which multiple well-designed human studies have demonstrated a lack of efficacy or unacceptable safety profiles
Freiherr J, Hallschmid M, Frey WH, Brunner YF 2nd, Chapman CD, Holscher C, et al
Wegovy is a once-a-week injection that can help with weight loss and lower the risk of cardiovascular events in people with a history of heart disease
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