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Luteolin attenuates the chemoresistance of osteosarcoma through inhibiting the PTN/-catenin/MDR1 signaling axis by upregulating miR-384
MTHFR mutations can also cause high levels of homocysteine in the blood, which generate a range of cardiovascular symptoms, including high blood pressure (x)
Both of these studies used mutant cells that were compromised in their ability to respond to ER stress
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