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Epigenetics, the ENCODE project and T1D Epigenetic modifications, such as DNA methylation and post-translational histone modifications are indispensable for a variety of genomic processes, including maintenance of genomic integrity and regulation of gene expressions

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Under oxidative stress, these residues are prone to oxidation in sulfenic acid, which efficiently reacts with GSH leading to form GSSG which is catalytically reduced back to GSH by the NADPH dependent glutathione reductase (GR)

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