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The nitrogen atoms on the histidine imidazole ring and glycine amine backbone coordinate with Cu with extremely high binding affinity, forming a stable bioavailable chelate complex
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In-vitro fibroblast studies indicate that GHK-Cu upregulates transcription of collagen and elastin genes and supplies copper as a cofactor for lysyl oxidase, the enzyme that cross-links these matrix proteins
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GHRP-2 (Growth Hormone Releasing Peptide) is a 2nd-generation Growth Hormone Secretagogue (GSH)
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