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Cells pre-treated with carfilzomib (1 h), and then treated with indicated compounds (10 nM dBET6, 2 M dHTC3 and 2 M epi -dHTC3, 3 h) and 100 nM TAMRA-CA

Roesel RA, Hommes FA, Samper L: Pyroglutamic aciduria (5-oxoprolinuria) without glutathione synthetase deficiency and with decreased pyroglutamate hydrolase activity