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One storage trade-off: NaCl can speed aggregation in the vial over weeks. Mix smaller amounts and use within 12 weeks

Hydroxocobalamin: Adverse reactions (IV use)

Side Effects: Published Phase 1/2 data on CJC-1295 alone reported mild facial flushing post-injection in some participants and no serious adverse events at studied doses (Teichman et al., PMID 16352683)

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D+Q works by inhibiting pro-survival pathways (tyrosine kinases and Bcl-2 family) broadlythese pathways are also present in non-senescent cells, creating off-target effects