These results suggest that the uptake of GLP-1RAs into the brain via tanycytes is important for their anti-obesity effects
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Efficacy of semaglutide in a subcutaneous and an oral formulation, Frontiers in Endocrinology (2021) Oral or injectable semaglutide for the management of type 2 diabetes in routine care: A multicentre observational study comparing matched cohorts, Diabetes, Obesity , & Metabolism (2024) Effectiveness of oral versus injectable semaglutide in adults with Type 2 diabetes: Results from a retrospective observational study in Croatia, Diabetology (2024) Drug absorption, Merck Manual Rybelsus label, U.S
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Results Trial population Of 62 screened individuals, 49 (29 males and 20 females) were randomized and were exposed to trial drug