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Without DAC, you need multiple daily injections to maintain elevated GH levels, typically 2 to 3 times per day

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However, this equation includes a race coefficient that may overestimate eGFR in non-Hispanic Black individuals and underestimate CKD prevalence compared with the newer CKD-EPI 2021 equation, which removes race adjustment and is recommended by current KDIGO guidelines

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doi: 10.4103/ijem.ijem_522_21

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