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Alcohol-related problems often have downstream effects on mood and anxiety, so we expected the effect to be positive on these as well. However, the magnitude of the association surprised the researchers: Because this is a registry-based study, we cannot determine exactly why or how these medications affect mood symptoms, but the association was quite strong
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The brain, sensing a drop in blood pressure and oxygen, initiates a "fight or flight" surge of adrenaline and norepinephrine, which causes the rapid, pounding heart rate (tachycardia), severe lightheadedness, and physical tremors associated with orthostatic intolerance
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