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Is AOD 9604 safe for patients with diabetes or insulin resistance
Presented for research literature review only Borvinskaya EV et al
April 11, 2018
At the gene level, GHK-Cu modulates a large share of the human transcriptome: an influence on roughly 31.2 percent of genes at a change of at least 50 percent is reported, of which about 59 percent are upregulated and 41 percent downregulated, with upregulation of about 84 DNA repair genes and ubiquitin-proteasome genes as well as suppression of proinflammatory signals such as IL-6 and NF-kB-driven TNF Pickart et al., 2018
The molecule consists of a corrin ring coordinated to a central cobalt ion with a cyano ligand at the upper axial position and a 5,6-dimethylbenzimidazole nucleotide at the lower axial position
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