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As such, secondary outcomes include changes in cognition, disease severity and function before and after treatment and across the one-year study period and measures of senescence and AD biomarkers in CSF pre- and post-treatment (baseline and three months) with an optional end of study collection
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Most transaldolase deficient patients will be associated with dysmorphic features, congenital heart defects, and hemolytic anemia
7.3.2 Research priority identification Critical research needs include long-term field studies spanning multiple years and diverse environmental conditions, mechanistic toxicity studies elucidating cellular and molecular mechanisms of nanoparticle effects, and ecosystem-level studies examining community and population-level responses to chronic exposure (Meng et al., 2025)
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