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But millions of Americans struggle with varying degrees of obesity, and the causes are diverse yo-yo dieting strategies, challenges accessing healthy food at an affordable price, individual biological and genetic factors, how our brains are wired, and widespread mental health and substance abuse issues

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14 , eabg4132 (2022)

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Discuss these challenges openly with your healthcare providerthey may be able to suggest solutions such as different injection techniques, strategies for managing side effects, or in some cases, alternative treatment options that better align with your lifestyle

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Second, the current studies largely rely on cellular and animal models, whereas human colonic organoids may be more suitable since they are more physiologically relevant and better simulate the epithelial microenvironment

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2025;Volume 162025

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