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Br J Clin Pharmacol (2018) 84(9):202939
Metabolic rebound after GLP-1 receptor agonist discontinuation: a systematic review and meta-analysis
GLP-1 has a very short half-life of approximately 1-2 minutes in circulation, as it is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4)
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