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For the phenol estimation, 500 L of the supernatant was mixed with 2.5 mL of FolinCiocalteu reagent (diluted ten times with distilled water) and incubated at room temperature for 5 min

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The protocol of the target RCT and the details of emulation are summarized in Supplement Table 1

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CrossRef Odanacatib Inhibits Resistin-induced Cardiomyocyte Hypertrophy Through the Inactivation of ERK Signaling Pathway Xian Zheng, Guanchang Cheng, Jianwei Luo, Qunhui Ye, Yongzhi Deng, Lin Wu International Journal of Pharmacology.2017

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In subsequent weeks, this effect dropped to 61.5% [263]

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