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SIRT3 deacetylase activity confers chemoresistance in AML via regulation of mitochondrial oxidative phosphorylation

(More information) Evidence from randomized controlled trials suggests that L-carnitine or acylcarnitine esters may be useful adjuncts to standard medical treatment in individuals with cardiovascular disease

Individuals with active cancer, sirtuin-related conditions, or those taking medications targeting NAD pathways should consult a provider before starting either compound

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Kennedy L, Sandhu JK, Harper M-E, Cuperlovic-Culf M