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Both animal and human studies demonstrate that LPS stimulate GLP-1 release via Toll-like receptors (TLRs)

Prescription GLP-1 receptor agonists may be indicated for adults with type 2 diabetes not meeting glycemic targets, those with established cardiovascular disease or chronic kidney disease, or individuals with obesity and weight-related complications when lifestyle interventions prove insufficient

& Centre for Research Excellence in Diabetic Retinopathy Study Group

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Risk of death among users of proton pump inhibitors: a longitudinal observational cohort study of United States veterans