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The inhibition of GPX4 leads to the accumulation of lipid peroxides and the generation of ROS 46
Faghihkhorasani F, Moosavi M, Rasool Riyadh Abdulwahid AH, et al
Unreconstituted vials: can be stored at room temperature before mixing, but refrigeration is preferred
If irritation continues to occur, apply an over-the-counter itch cream, preferably with hydrocortisone, or discontinue use
The cleavage profile we observed for the protease was consistent with our observations of X(PC) in vitro cleavage, with procaspase-1 enriching in the top 97.8% of substrates (log 2 (fold enrichment) = 2.68) and IL-1 enriching in the top 83.5% of substrates (log 2 (fold enrichment) = 1.05
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