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Patients taking semaglutide also had fewer heart failure events and were hospitalized less often, compared to those on placebo, according to the trials

early metabolic improvements are promising, but definitive cardiovascular risk-reduction data were not established at the time of this writing

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The same volume of Cytotox-ONE Reagent (Promega, USA) was added into each well and the microplate was shaken for 30 secs to mix