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Weiss wrote in a caption: "The biggest thing I've noticed since taking retatrutide is the fact that it's a challenge to actually gain fat not gain weight, but gain body fat." Becerra ("not a bodybuilder by any means at all, but I do like to look good with my shirt off") bought himself a substance labeled "retatrutide" online, a powder mixed with water, and injected it into his muscles with a syringe, just as Weiss and other bodybuilders online described

Ongoing research is evaluating whether future GLP-1 medications may reduce these effects

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It is tempting to buy large quantities when a trusted vendor has a good price, but lyophilized peptides, while stable for years at -20 degrees Celsius, are not infinitely shelf-stable