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The commercial success of GLP-1 receptor agonists such as Ozempic, Wegovy, and Rybelsus, along with dual GIP/GLP-1 receptor agonists including Mounjaro and Zepbound, has significantly increased the requirement for large-scale, high-quality peptide API manufacturing

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As we proceeded with the study, we found that even the dose of basal insulin could be reduced or eliminated altogether in a majority of these patients

The trial, which seeks to enroll 1,000 long COVID patients nationwide, will explore how self-administration of tirzepatide, Eli Lillys GLP-1 agonist marketed as Mounjaro for diabetes treatment and Zepbound for weight loss, affects symptoms over a 12-month period