glp 1 weight loss mechanism The of GLP-1 to [12] GLP-1 vs. Lifestyle Changes: What

Bergmann NC, Davies MJ, Lingvay I, Knop FK

doi: 10.1161/hypertensionaha.115.06017 83

Artificial intelligence can support target identification, clinical trial design, biomarker discovery, patient stratification, real-world evidence generation, and safety monitoring

Furthermore, the study carefully selects trials that focus exclusively on the GI adverse effects of GLP-1 RA in RCTs involving adults with overweight or obesity

One phase 3 clinical trial found that survodutide led to an average 12% to 18.7% body weight reduction , depending on dose, in adults with obesity and without diabetes after 76 weeks compared to 5% in the placebo group