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It is currently completing Phase 3 TRIUMPH trials and is available for research use in lyophilized (freeze-dried powder) form for the latest on [when retatrutide will be FDA approved](/guides/retatrutide-fda-approval-2026-timeline-status), see our regulatory timeline tracker
Low blood glucose, called hypoglycemia, is more likely when sitagliptin is used with insulin or medicines that increase insulin release
Although the shortage has largely been resolved, occasional supply issues persist at some pharmacies
Column chromatography of proteins: Substituted cellulose
GLP-1 agonists slow down your digestive system, thus reducing hunger and making you feel fuller faster, however, that favorable mechanism comes with some gastrointestinal side effects
