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Limitations of the Current Evidence Lack of Human Clinical Data: Despite an extensive body of preclinical research, there are very few human trials
In the Reynolds et al
In experiments with hFOB1.19 cells, MOTS-c treatment increased cell viability in a time-dependent manner and upregulated mRNA and protein expressions of TGF-, SMAD7, COL1A1, and COL1A2
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