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For anyone who is peptide curious, skeptical, or anti-peptides (that are not studied with randomized control trials) as well as people who are very pro peptides will benefit from listening to the episode

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in the context of major depression, SSRI treatment reverses both astrocytic atrophy and the decrease in astrocyte numbers in animal models

Protein kinase A, in turn, activates cAMP responsive element-binding protein 1, which translocates from the cytosol into the nucleus (Tengan et al., 2012)