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Interactions: Inform patients that certain drugs (antibiotics, methotrexate) can affect B12 testing, but generally B12 injections have no major drug interactions
Distribution patterns Once absorbed, the distribution of these compounds throughout the body significantly impacts their therapeutic effects
However, if a person is unaware that their supplement has expired, they may believe they are consuming more nutrients than they are
Whether cycling is necessary from a safety perspective remains unknown
The standard schedule is a starting point, not a strict rule The 2024 NICE guideline NG239 on B12 deficiency in over 16s makes an important point: the optimal route, dose and frequency of B12 replacement have never been firmly established, and have often followed custom and historical practice
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