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As expected, administration of BSO in the established high ACTL6A-expressing PDX tumors (cases 1 and 3) attenuated tumor progression

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The researchers then looked at whether women were diagnosed with a new breast cancer in two different cohorts: the full group of 111,646 women and a smaller cohort of 30,528 women, including one-to-one controls for each of the 15,264 GLP-1 cases, matched across age, race, ethnicity, BMI, breast density, and diabetes status to limit bias and potential confounding

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Both anti-diabetic treatments function by playing key modulatory roles in the incretin system

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