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Glutathione is widely studied in cell and laboratory work, but oral glutathione has poor bioavailability, and the value of injectable glutathione for raising tissue levels or producing clinical benefits is not well established [11] [12]
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The resulting GSH or homoglutathione (-L-glutamyl-L-cysteinyl--alanine) conjugates were usually much less toxic and more water-soluble than the original xenobiotics (Brown and Neighbors, 1) (Bartling et al., 2002
However, once a vial is punctured, its shelf life dramatically shortens
GST catalyzes the GSH-mediated hydrolysis of sulfonamide bonds, releasing GST competitive inhibitors such as benzylsulfonyl-GSH or S -benzyl-GSH (Koeplinger et al., 1999
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