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Increased levels of oxidative stress, malnutrition, or increased toxic burden can also result in an increased need for glutathione and thus a lower GSH status
The -Cu denotes that bound copper
Safety, tolerability, access, cost, and individual response all play important roles
What these mechanisms do NOT prove: That any of this occurs in humans at the doses found in commercial capsules
Dose-dependent cytotoxicity is pronounced, as high concentrations disproportionately reduce cell viability, and even low doses of small NPs (e.g., 18 nm) trigger significant toxicity (Gandamalla et al., 2019
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