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Mechanical cues: bidirectional reciprocity in the extracellular matrix drives mechano-signalling in articular cartilage
NNMT activity increases with age, obesity, and metabolic dysfunction
GHK (glycyl-l-histidyl-l-lysine) is an endogenous tripeptide isolated from plasma, which can coordinate with the organic cation Cu 2+ to form a copper peptide (CuP) complex 33,34
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doi:10.1016/j.brs.2020.11.014
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