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In addition, both TTP and gAgAP downregulated transcription levels of angiotensin II receptor type 1 ( agtr1 ) and miR-132/-212, with TTP producing a comparable reduction in agtr1 to captopril and a significant decrease in miR-132/-212 expression

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The reaction can be generalised as such: 1 -amino acid + R 2 --ketoacid R 1 --ketoacid + R 2 -amino acid A very common -keto acid is -ketoglutarate, an intermediate in the citric acid cycle

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