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Mechanical forces applied to connective tissues alter the gene expression pattern and activity of fibroblasts, as mechanical signals are converted into intracellular signalling events, a process called mechanotransduction
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Overall, the findings suggest potential benefits of GLP-1RA treatment in this high-risk population, although residual confounding and heterogeneity across autoimmune diseases mean the results should not be interpreted as proof of causality
Address underlying conditions Treatment depends entirely on the identified cause: Liver disease: Management according to aetiology (alcohol cessation, antiviral therapy for hepatitis, treatment of non-alcoholic fatty liver disease)
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