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Oncotarget (2016) 7:8107789
Importantly, proteolytic cleavage of SPARC (secreted protein acidic and rich in cysteine), a matricellular protein abundantly expressed at sites of vascular injury and tissue remodeling, generates GHK-containing fragments that promote endothelial cell proliferation and neovascularization
That trial history is routinely cited in marketing for TB-500, which was not the investigational agent in any of it
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LL-37: A host defense peptide with clinical potential
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