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N Engl J Med (2015) 373(23):224757
Additionally, GLP-1 promotes the growth and proliferation of pancreatic cells, inhibits glucagon secretion, and enhances glucose uptake in peripheral tissues, making it a crucial factor in maintaining blood glucose stability
In AD mouse models, pathophysiological changes, such as anti-apoptotic effects, reduced A deposition and phosphorylated hippocampal tau, protection from synapse loss, reduced inflammatory and oxidative stress response in the cortex and hippocampus, and increased BDNF have been observed [119,120,121]
Their minuscule scale allows them to access areas that are challenging for traditional diagnostic and therapeutic tools, such as the pancreatic duct (24 mm), blood vessels [57, 58], and even individual cells [59,60,61]
Wang X, Huycke MM
