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Symptoms are typically dose-related and occur early in treatment, with many patients seeing improvement within a few weeks as the body adapts to slower gastric emptying and central effects
Evidence quality: Mechanistic (human) + Phase II exploratory
It usually happens within minutes or hours after the first dose
These in turn are claimed to stimulate production of GLP-1, the gut hormone associated with satiety that Ozempic-like drugs are mimicking
Every fresh line could trigger past concern about taking too little or not observing rapidly enough
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