The most common adverse effects of GLP-1 receptor agonistsnausea, vomiting, diarrhea, and constipationoccur in 20-50% of patients in general populations
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Altered intestinal permeability has been shown to occur in asymptomatic patients before the onset of clinical symptoms [95, 99, 100]
European Journal of Nutrition vol
These benefits include reductions in cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke, as shown in landmark trials such as LEADER (liraglutide), SUSTAIN-6 (semaglutide), and REWIND (dulaglutide)