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Equillium (NASDAQ: EQ) shares plummeted 38% from $1.38 to 86 cents Thursday after the company said collaboration partner Ono Pharmaceutical let lapse its option to acquire Equilliums rights to itolizumab, a monoclonal antibody targeting the CD6-ALCAM signaling pathway, which plays a key role in modulating effector T cells that drive numerous immuno-inflammatory diseases

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