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However, a significant proportion of patients are still refractory to pharmacological treatments, so the development of new drugs targeting the underlying mechanisms of UC is necessary to achieve optimal disease control
Open Med
Patients will naturally choose the least invasive option first
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To test our hypothesis, we first detected GCLC expression and found that when NRF2 was knocked down, the inhibition of GCLC expression by ACTL6A KD was diminished
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