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SURPASS-4, a multicenter open-label RCT comparing treatment with tirzepatide and insulin glargine in T2D patients at increased CV risk for a median of 85 weeks, was the only study in the SURPASS program to include the change from baseline in eGFR and UACR and occurrence of eGFR decline of at least 40%, renal death, progression to end-stage kidney disease or new-onset MA among the prespecified analyses [48]

Confirming coverage and completing any prior authorization requirements in advance can save time and hassle

Niacinamide: Niacinamide, or vitamin B3, is a powerful antioxidant that improves the skin's barrier function, evens out skin tone and reduces the appearance of pores

Tirzepatide can be used with other diabetes medications, but patients taking insulin or sulphonylureas may need dose reductions to reduce hypoglycaemia risk

It is prepared to the specifications set by the prescriber for the individual patient