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Notably, the authors suggested that semaglutide may reduce de novo collagen synthesis without causing degradation of pre-existing collagen fibers [29], implying that semaglutide may not improve existing fibrosis, but it may prevent the initiation and progression of fibrosis, which, however, needs other more focused studies to be definitively demonstrated
Neither author has received support of any kind for the preparation of this article
Other modalities Moderna is pursuing in discovery include intravenous (IV) systemic therapeutics, IV liver therapeutics and inhaled pulmonary therapeutics
