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GLP-1 agonists are being used in combination with basal insulin (Dungan & DeSantis, 2016), although this is not an FDA-approved indication (see rxlist.com) they should not be used as a substitute for basal insulin, as this has been found to result in a decline in glycemic control)(Dungan & DeSantis, 2016) Clinical trials indicate it can reduce HbA1c by ~0.8% Undergoes renal clearance, with dosage reduction needed if creatinine clearance falls to 1.5
Secondary endpoints The incidence of in-stent restenosis was 2.78%in the GLP-1RA group and 11.54%in the control group ( P = 0.028)
Fat loss follows as a downstream effect
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