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Specifically, these mechanisms of action cover multiple aspects, such as activation of the cAMP-PKA signaling pathway, inhibition of pro-inflammatory cytokine release, and also activation of the AMPK signaling pathway, promoting the expression of anti-inflammatory genes, and regulation of macrophage function [26]
On the other hand, bronchial epithelial cells, lymphocytes and dendritic cells also play an active role in asthma
More than 95% of it is stored in muscles and trace amounts are found in blood, heart, liver, and kidneys
This review explores the potential of flavonoids as miRNA modulators, focusing on their ability to regulate miRNAs associated with cardiac fibrosis, hypertrophy, and vascular inflammation
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