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These include the use of phosphodiesterase type 5 inhibitors, medications like amiodarone and cabergoline, as well as smoking, obesity, obstructive sleep apnea, small optic nerve cup (also referred to as disc at risk), optic nerve drusen, and hypertension
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Patients often describe steadier energy, clearer focus, and less inflammation
The drugs lack of efficacy in this context does not preclude its potential utility in the broader, more heterogeneous population of older adults experiencing cognitive decline, where vascular and metabolic factors frequently play a major role
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