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Cluster analysis reveals a homogeneous subgroup of PCOS women with metabolic disturbance associated with adverse reproductive outcomes

Ba DM, Ssentongo P, Beelman RB, Muscat J, Gao X, Richie JP

The observed effects in maximal respiration and reserve capacity most likely occur due to increased glycolysis and consequent augmented flux of pyruvate into the Krebs cycle

Interestingly, in some cells of the ARC nucleus, it is also possible to find neuropeptide receptors (molecules with a role in the regulation of calorie intake) together with GIP-R, probably implicated in the regulation of food intake