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Environ Microbiol Rep 13:428444

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Muscle pain from protein deficiency and muscle catabolism may take one to two weeks to improve after protein intake is optimized

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The GLP-1 data presented to date are based on: Large observational cohort studies Retrospective comparative effectiveness analyses Meta-analytic pooling of observational datasets They are not yet based on dedicated randomized clinical trials designed specifically to evaluate colorectal cancer incidence or adenoma prevention as primary endpoints

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That said, clinical guidance exists for transitioning between the two

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